Measure Twice, Cut Once

Re: Measure once or twice--does it really matter?

The editorial (1) on our article (2) makes a number of points, and we wish to address these with some further explanation. The first clarification concerns our theoretical section. Our argument is, in fact, more pragmatic rather than mathematical and is indeed the point that the editorial identifies as " largely due to difference in scales. " From its definition as an x% reduction, any measure ...

Measure twice, cut once: attachment theory and the NICHD Study of Early Child Care and Youth Development.

The NICHD Early Child Care Research Network has produced research findings that provide reassuring confirmation of some central tenets of attachment theory, challenges to other aspects of the theory, and above all highlight the need for attachment researchers to clarify the claims for which the theory can be held accountable. This commentary on Friedman and Boyle's excellent review evaluates th...

Once bitten, twice shy.

Once-Weekly Exenatide Versus Once- or Twice-Daily Insulin Detemir

OBJECTIVE This multicenter, open-label, parallel-arm study compared the efficacy and safety of exenatide once weekly (EQW) with titrated insulin detemir in patients with type 2 diabetes inadequately controlled with metformin (with or without sulfonylureas). RESEARCH DESIGN AND METHODS Patients were randomized to EQW (2 mg) or detemir (once or twice daily, titrated to achieve fasting plasma gl...

Measure aspects of cut